脑血管病的急救与介入治疗
教授
(1)Ren C, Gao X,Steinberg, Zhao H*. Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning. Neuroscience. 2008;151(4):1099-103. IF=2.494
(2)Ren C, Gao X, Niu G, Yan Z, Chen X, Zhao H*. Delayed Postconditioning Protects against Focal Ischemic Brain Injury in Rats. PLoS ONE. 2008; 3(12): e3851.
(3)Zhang H, Ren C, Gao X, Takahashi T, Spolsky RM, Steinberg GK, Zhao H*. Hypothermia blocks beta-catenin degradation after focal ischemia in rats.Brain Res. 2008 ;1198:182-7.
(4)Gao X,Ren C, Zhao H*. Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning.J Neurosci Res. 2008 ;86(11):2505-11.
(5) Zhang H,Gao X,Yan Z, Ren C, Shaimohata T, Steinberg GK, Zhao H*. Inhibiting caspase-3 activity blocks beta-catenin degradation after focal ischemia in rat. Neuroreport. 2008 ;19(8):821-4.
(6) Bai YH, Ren CC*, Gong XR, Meng LP.A maternal hereditary deafness pedigree of the A1555G mitochondrial mutation, causing aminoglycoside ototoxicity predisposition. J Laryngol Otol. 2008 Oct;122(10):1037-41.
(7) Ryu EK, Wu Z, Chen K, Lazarus LH, Marczak ED, Sasaki Y, Ambo A, Salvadori S, Ren C , Zhao H, Balboni G, Chen X*. Synthesis of a Potent and Selective (18)F-Labeled delta-Opioid Receptor Antagonist Derived from the Dmt-Tic Pharmacophore for Positron Emission Tomography Imaging. J Med Chem. 2008 ;51(6):1817-23.
(8)Ren C, Yan Z, Wei D, Gao X, Chen X, Zhao H*. Limb remote postconditioning protects against focal ischemia in rats. Brain Res. 2009 Sep 8;1288:88-94.
(9)Wei D, Ren C,Chen X, Zhao H*(Co-first author). The Chronic Protective Effects of Limb Remote Preconditioning and the Underlying Mechanisms Involved in Inflammatory Factors in Rat Stroke. PLoS ONE,2012;7(2):e30892.
(10)Zhao H*, Ren C, Chen X, Shen J. From Rapid to Delayed and Remote Postconditioning: The Evolving Concept of Ischemic Postconditioning in Brain Ischemia. Curr Drug Targets. 2012 ; 13(2): 173–187.
(11)Jin Z, Shi L, Wang YJ, Yang LG, Shi YH, Shen LW, Ren CC*.Prevalence of headache among children and adolescents in Shanghai, China.J Clin Neurosci. 2013 ;20(1):117-21.
(12)Duan S, Shao G, Yu L, Ren C(corresponding author).Angiogenesis contributes to the neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats. Int J Neurosci. 2015;125(8):625-34.
(13) Guo T, Li H, Lv Y, Lu H, Niu J, Sun J, Yang GY, Ren C, Tong S(Co-corresponding author). Pulsed Transcranial Ultrasound Stimulation Immediately After The Ischemic Brain Injury is Neuroprotective.IEEE Trans Biomed Eng. 2015 Oct;62(10):2352-7.
(14)Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC(corresponding author).Telerehabilitation Approaches for Stroke Patients: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2660-8.
(15)Jin W, Chen J, Shi F, Yang W, Zhang Y, Liu Y, Dong W, Jin Y, Ma W, Ma Z, Min X, Jin Y, Gu Y, Ren C(corresponding author).Home-based tele-supervising rehabilitation for brain infarction patients (HTRBIP): study protocol for a randomized controlled trial. Trials. 2015 Feb 25;16:61.
(16)Duan S, Zhang S, Li L, Ren C(corresponding author)Xie J.Cariod antery intima-media thickness associated with prognosis of intracranial branch atheromatous disease. Int J Neurosci. 2017 ;127(4):361-367.
(17)Jin W, Xu W, Chen J, Zhang X, Shi L, Ren C(corresponding author). Remote limb preconditioning protects against ischemia-induced neuronal death through ameliorating neuronal oxidative DNA damage and parthanatos. J Neurol Sci. 2016 Jul 15;366:8-17.
(18)Jin W, Xu W, Chen J, Zhang X, Shi L, Ren C(corresponding author).Adenosine kinase facilitated astrogliosis-induced cortical neuronal death in+D5 traumatic brain injury. J Mol Histol. 2016 Jun;47(3):259-71.
(19)Chen J,Jin W, Dong WS, Jin Y, Qiao FL, Zhou YF, Ren CC(corresponding author). Effects of Home-based Telesupervising Rehabilitation on Physical Function for Stroke Survivors with Hemiplegia: A Randomized Controlled Trial. Am J Phys Med Rehabil. 2017 Mar;96(3):152-160.
(20)Xu W, Jin W, Zhang X, Chen J, Ren C(corresponding author).Remote Limb Preconditioning Generates a Neuroprotective Effect by Modulating the Extrinsic Apoptotic Pathway and TRAIL-Receptors Expression. Cell Mol Neurobiol. 2017 Jan;37(1):169-182.
(21) Chen J, Sun D, Yang W, Liu M, Zhang S, Peng J, Ren C(corresponding author). Clinical and Economic Outcomes of Telemedicine Programs in the Intensive Care Unit: A Systematic Review and Meta-Analysis. Journal of Intensive Care Medicine.2017;33(7): 383–393.
(22)Chen J, Sun D, Liu M, Zhang S, Ren C(corresponding author). Defibrinogen Therapy for Acute Ischemic Stroke: 1332 Consecutive Cases. Scientific Reports.2018;8(1):9489.
(23) Liu M, Chen J,Zhang S, Ren C(corresponding author) Downregulation of lipocalin-2 and Bim expression after remote limb preconditioning in the ischemic rat brain. Brain Res. 2018;1679:1-9. IF=3.125
(24) Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC (corresponding author).Three Stages of Evolution in the Treatment of Acute Ischemic Stroke: Stroke Unit Care, Intravenous Thrombolysis and Endovascular Therapy. Journal of Neurology and Neurological Disorders. 2018;3(3):306.
(25) Chen J, Liu M, Sun D, Jin Y, Wang T, Ren C(corresponding author).Effectiveness and neural mechanisms of home-based telerehabilitation in patients with stroke based on fMRI and DTI: A study protocol for a randomized controlled trial. Medicine . 2018 Jan;97(3):e9605. 2.028
(26) Chen J, Sun DL, Shi YH, Jin W, Wang YB, Xi Q, Ren C(corresponding author). Alterations of static functional connectivity and dynamic functional connectivity in motor execution regions after stroke. Neuroscience Letters.2018;686: 112–121.
(27) Chen J, Sun D, Shi Y, Jin W, Wang Y, Xi Q , Ren C(corresponding author).Dynamic Alterations in Spontaneous Neural Activity in Multiple Brain Networks in Subacute Stroke Patients: A Resting-State fMRI Study. Front. Neurosci. 2019; 12:994.
(28) Yang X, Zhang S, Dong Z, Zi Y, Luo Y, Jin Z, Shi L, Li C, Ren C and Wu D (corresponding author)Insulin Resistance Is a Risk Factor for Overall Cerebral Small Vessel Disease Burden in Old Nondiabetic Healthy Adult Population. Front. Aging Neurosci. 2019;11:127.
(29) Jin W,Xu W,Zhang XX, Ren C(corresponding author).Ischemic Preconditioning Upregulates Decoy Receptors to Protect SH-SY5Y Cells from OGD Induced Cellular Damage by Inhibiting TRAIL Pathway and Agitating PI3K/Akt Pathway. Molecular Neurobiology (2020) 57:3658–3670.
(30) Chen J, Sun DL,Zhang SF,Shi YH,Qiao FL,Zhou YF,Liu J, Ren C(corresponding author).The effects of home-based telerehabilitation in stroke patients: a randomized controlled trial. Neurology. 2020 Oct 27;95(17):e2318-e2330.
(31) Chen J,Sun DL,Shi YH,Jin W,Wang YB,Xi Q, Ren C(corresponding author) Altered static and dynamic voxel-mirrored homotopic connectivity in subacute stroke patients: a resting-state fMRI study. Brain Imaging and Behavior. 2021 Feb;15(1):389-400.
(1) 远隔预处理诱导缺血脑保护的血管生成机制研究。
(国家自然科学基金,课题编号: 81071061)。
(2)缺血性脑中风及其康复过程中的神经信息传导网络的可塑性研究。
(国家自然科学基金,课题编号: 61001015,与上海交通大学合作项目)。
(3)远隔预处理诱导缺血脑保护的蛋白质组研究。
(上海市科委,课题编号: 10411968900)。
(4)长程视频脑电监测对睡眠障碍的分型诊断与治疗研究。
(上海市科委重大专项子课题,课题编号:11DZ192130B)
(5)缺血脑血管病急性期危险分层对复发预测的对比分析。
(闵行区科委,课题编号: 2011MHZ15)
(6)高压氧预处理诱导缺血脑保护的血管生成机制研究。
(上海市卫生局,课题编号: 2009046)
(7)缺血预处理对肌肉组织的保护研究。
(上海市卫生局,课题编号:2009044)
(8)上海市健康网云计划基于EHR构建居家远程诊疗系统。
(上海市科委重大项目子课题,课题编号: 11DZ1500104)
(9)基于物联网技术进行居家远程瘫痪康复的示范应用。
(上海市第二批战略性新兴产业重大项目,课题编号:2013SJXW152)
(10)脑缺血半暗带区抗凋亡--凋亡转化的关键调控研究。
(上海市卫生局重点专科建设课题,课题编号:ZK2012B02-1)
(11)不同类型睡眠障碍患者的物理干预方式研究。
(上海市科委重点项目子课题,课题编号:12DZ1940906)
(12)Che-1在远隔与处理诱导缺血脑保护的作用研究。
(“985三期”重点学科、交叉学科优秀博士生科研资助计划)
(13)缺血远隔后处理诱导脑保护的蛋白质组与基因组研究。
(上海市卫生局新百人项目配套课题,项目编号:XBR2011011)
(14)脑卒中偏盲病人康复的视觉注意训练机理研究。
(上海市卫生局重点专科建设课题,课题编号:ZK2012B02-2)
(15)脑缺血的TRAIL凋亡途径研究。
(闵行区科委,课题编2010MHZ019)
(16)远隔预处理诱导缺血脑保护的差异表达基因研究。
(闵行区科委,课题编号: 2011MHZ07)
(17)家庭监护设备的临床实验和试点应用。
(上海市科委重点项目子课题,课题编号:12DZ1941103)
(18)dMCAO脑缺血模型新发现MRI异常信号与病理对照研究。
(复旦大学青年基金,课题编号: 10L-31)
(19)凋亡拮抗转录因子AATF介导远隔预处理诱导缺血脑保护的作用机制研究。
(国家自然科学基金,课题编号: 81571277)
(20)物联网智慧养老技术标准。
(上海市经信委创新专项,JJ-YJCX-01-16-1545)
(21) TRAIL及其受体介导远隔预处理诱导缺血脑保护的作用机制研究。
(同济大学,项目编号:22120180334)
(22)项目名称:远隔预处理调控TRAIL-DcR1/DcR2诱导脑保护的机制研究 ,
(国家自然科学基金,项目编号:82060227)
复旦大学"优秀导师"
脑血管病的基础与临床研究